A T-type calcium channel required for normal function of a mammalian mechanoreceptor
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A T-type calcium channel shapes how a mammalian mechanoreceptor responds to touch, mapped with calibrated displacements from a computer-controlled Kleindiek Nanomotor.
The authors show that a T-type calcium channel shapes the sensitivity of a specific mammalian mechanoreceptor. Working in an ex-vivo skin–nerve preparation, they apply standardized displacement stimuli to a receptive field with a probe fixed to a computer-controlled Kleindiek Nanomotor, correlating the channel’s activity with the receptor’s mechanical responses.
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